Rag2-KO/hVEGFR2
모델명
C57BL/6Smoc-Kdrtm2(hKDR)Rag2em1Smoc
카탈로그
NM-HU-200280
모델 상태
Embryo cryopreservation
유전자 요약
Official Symbol
Rag2
Official Symbol
KDR
모델 설명
검증 데이터
Fig1. In vivo anti-tumor response of Cyramza and Avastin in the treatment of gastric cancer PDX model(GA2419)in the immunodeficient Rag2-KO/hKDR mice. (Completed in collaboration with CrownBio)
(A)Breeding scheme for development of Rag2-KO/hKDR mice; (B) Tumor growth curves upon treatment of Cyramza and Avastin; (C) Body weight change upon treatment.
Fig2. In vivo anti-tumor response of Cyramza in thetreatment of liver cancer PDX model(LI0612)in the im-munodeficient Rag2-KO/hKDR mice. (Completed in collaboration with CrownBio)
(A)Tumor blood vesselstaining via anti-human VEGFR2 IHC; (B) Tumor growth curves upon Cyramza treatment; (C)Body weight change upon treatment.
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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