Ccr2-KO

모델명

C57BL/6Smoc-Ccr2em1Smoc

카탈로그

NM-KO-190018

모델 상태

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유전자 요약

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Ccr2

모델 설명

This Ccr2 knockout mouse model was generated by knocking out the exon 3 region of the Ccr2 .
신청분야:Immune-related

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Fig1. Validation of Ccr2 gene expression by RT-PCR.(A) Schematic diagram of primer design; (B) No product was obtained from Ccr2 knockout homozygous mice, and the wild-type mice could obtain the 824bp target PCR product. (M, DNA marker; HO, homozygous; WT, wild type)


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Fig2. Validation of  CCR2 expression in the bone marrow by FACS. CCR2 expression could not be detected on CD11b+ cells of the Ccr2 knockout homozygous mice. 


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Fig3. Validation of CCR2 expression in the spleen by FACS. CCR2 expression could not be detected on CD11b+ cells of the Ccr2 knockout homozygous mice. 



당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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