Il10-KO

모델명

C57BL/6Smoc-Il10tm1.1Smoc

카탈로그

NM-KO-190426

모델 상태

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유전자 요약

Official Symbol
Il10

Synonyms

CSIF， Il-10

NCBI ID

16153

MGI ID

96537

Ensembl ID

ENSMUSG00000016529

Pubmed

Il10

Human Ortholog

IL10

모델 설명

This Il10 knockout strain is established by crossing Il10-CKO and Dppa3-Cre mice strains together. The Il10 flox mice possess loxP sites flanking exons 1 .
신청분야：immune system

검증 데이터

il10.png

Fig1 Expression of IL10 in the Serum of Il10-KO Homozygous mice is detected by Elisa.

IL10 eKO mice were treated with LPS(3mg/kg,i.p.). Mice were sacrificed 4h after injection, and serum samples were collected for Elisa.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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