hCD27(2)

모델명

C57BL/6Smoc-Cd27tm3(hCD27)Smoc

카탈로그

NM-HU-190035

모델 상태

Embryo cryopreservation

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유전자 요약

Official Symbol
CD27

Synonyms

Cd27; S152; Tnfrsf7; Tp55

NCBI ID

21940

MGI ID

88326

Ensembl ID

ENSMUSG00000030336

Pubmed

CD27

Human Ortholog

CD27

모델 설명

The endogenous mouse Cd27 gene was replaced by human CD27 gene. While hCD27 mice(Stock No.NM-HU-00093）have been pulled from shelves for some reasons.
신청분야：Immunotherapy,cancer research,drug screening

검증 데이터

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Fig1. Detection of hCD27 expression on T cells in spleen in heterozygous hCD27 kncokin mice.

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Fig2. Detection of hCD27 expression on T cells in peripheral blood in heterozygous hCD27 knockin mice.

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Fig3. Detection of hCD27 expression on T cells in bone marrow in heterozygous hCD27 knockin mice.

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Fig4. Detection of hCD27 expression on T cells in spleen in homozygous hCD27 knockin mice.

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Fig5. Detection of hCD27 expression on T cells in bone marrow in homozygous hCD27 knockin mice.

당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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