hIL21R

모델명

C57BL/6Smoc-Il21rtm1(hIL21R)Smoc

카탈로그

NM-HU-210031

모델 상태

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유전자 요약

Official Symbol
IL21R

Synonyms

NILR

NCBI ID

60504

MGI ID

1890475

Ensembl ID

ENSMUSG00000030745

Pubmed

IL21R

Human Ortholog

IL21R

모델 설명

The endogenous mice Il21r gene was completely or partially replaced by human IL21R gene via ESC targeting.
신청분야：inmmue therapy；drug screening

검증 데이터

image.png

Fig 1. Detection of IL21R expression on spleen-derived activated T cells and B cells in hIL21/hIL21R dKI mice.

Note. Splenocytes from C57BL/6 and homozygous hIL21R mice were stimulated with anti-mCD3 antibody in vitro.


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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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