hSIGLEC8(2)
모델명
C57BL/6Smoc-Siglecfem1(hSIGLEC8)Smoc
카탈로그
NM-HU-210033
모델 상태
Embryo cryopreservation
유전자 요약
Official Symbol
Siglecf
모델 설명
검증 데이터
Fig1. Strain specific SIGLEC8 expression analysis in homozygouse hSIGLEC8 mice by flow cytometry. Spleen derived eosinophils were collected and analyzed by flow cytometry with species-specific anti-hSIGLEC8 and anti-mSIGLEC-F antibody. hSIGLEC8 was detectable in hSIGLEC8 mice but not in WT mice, mSIGLEC-F was detectable in WT mice but not in hSIGLEC8 mice.
Fig2. Strain specific SIGLEC8 expression analysis in homozygouse hSIGLEC8 mice by flow cytometry. Eosinophils of PBMC were collected from WT and homozygouse hSIGLEC8 mice, and analyzed by flow cytometry with species-specific anti-hSIGLEC8 and anti-mSIGLEC-F antibody. hSIGLEC8 was detectable in a small proportion of eosinophils in hSIGLEC8 mice, and the mSIGLEC-F was not expressed.
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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