hIL18

모델명

C57BL/6Smoc-Il18tm1(hIL18)Smoc

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NM-HU-210038

모델 상태

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유전자 요약

Official Symbol
Il18

Synonyms

Igif; Il-18

NCBI ID

16173

MGI ID

107936

Ensembl ID

ENSMUSG00000039217

Pubmed

Il18

Human Ortholog

IL18

모델 설명

The endogenous mice Il18 gene was replaced by human IL18 gene.
신청분야：inmmue therapy；drug screening

검증 데이터

image.png

Fig1. Detection of IL18 expression in intestine, colon and spleen by RT-PCR. 

Wild type: only one band at 305 bp with primers F1/R1 (mIl18); Homozygous: only one band at 265 bp with primers F2/R2 (hIL18). 

Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of hIL18 expression in serum by ELISA (n=3). 

Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig3. Detection of mIL18 expression in serum by ELISA (n=3). 

Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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