hIL18BP

모델명

C57BL/6Smoc-Il18bpem1(hIL18BP)Smoc

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NM-HU-210039

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Il18bp

모델 설명

The endogenous mice Il18bp gene was replaced by human IL18BP gene.
신청분야:inmmue therapy;drug screening

검증 데이터

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Fig1. Detection of IL18BP expression in thymus and liver by RT-PCR. Wild type: only one band at 354 bp with primers F1/R1(mIl18bp);Heterozygous: one band at 354 bp with primers F1/R1(mIl18bp) and one band at 220 bp with primers F2/R2(hIL18BP); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig2. Detection of IL18BP expression in thymus and liver by RT-PCR.  Wild type: only one band at 354 bp with primers F1/R1(mIl18bp); Homozygous: only one band at 220 bp with primers F2/R2(hIL18BP);  Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig3. Detection of hIL18BP expression in serum by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

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Fig4. Detection of mIL18BP expression in serum by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

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Fig5. Detection of hIL18BP expression in serum by ELISA (n=3). Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

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Fig6. Detection of mIL18BP expression in serum by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type.


당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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