NVG-hIL15
모델명
NOD.Cg-PrkdcscidIl2rgem1SmocIl15em1(hIL15)Smoc
카탈로그
GM-NVG-210001
모델 상태
Repository Live
유전자 요약
Official Symbol
Il15
모델 설명
The endogenous mice Il15 gene was replaced by human IL15 gene.
검증 데이터
Human IL15 expression analysis
Fig 1. Human IL15 expression analysis in homozygous NVG-hIL15 mice by ELISA.
Fig 2. Humanized immune reconstitution levels and body weight growth curves in huPBMC-NVG-hIL15 mice.
Fig 3. Humanized immune reconstitution levels and body weight growth curves in huPBNK-NVG-hIL15 mice.
Fig 4. Efficacy evaluation of CD20-targeting antibody using Raji huPBNK model.
Fig 5. Functional protein detection in NK cells in the presence of anti-hCD20 antibody drug using Raji huPBNK model.
Fig 6. ADCC efficacy research in vitro using huPBNK model.
Fig 7. Body weight growth curves in γδT-NVG-hIL15 mice.
Fig 8. Survial rates in γδT-NVG-hIL15 mice.
Fig 9. Humanized immune reconstitution levels in γδT-NVG-hIL15 mice.
당신은 또한 좋아할 수 있습니다
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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