hIFNGR1/hIFNGR2

모델명

C57BL/6Smoc-Ifngr1em3(hIFNGR1)Ifngr2tm(hIFNGR2)Smoc

카탈로그

NM-HU-220003

모델 상태

Embryo cryopreservation

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유전자 요약

Official Symbol
IFNGR1

Synonyms

Ifgr; CD119; Ifngr; Nktar; IFN-gammaR

NCBI ID

15979

MGI ID

107655

Ensembl ID

ENSMUSG00000020009

Pubmed

IFNGR1

Human Ortholog

IFNGR1

Official Symbol
IFNGR2

Synonyms

Ifgt; Ifgr2

NCBI ID

15980

MGI ID

107654

Ensembl ID

ENSMUSG00000022965

Pubmed

IFNGR2

Human Ortholog

IFNGR2

모델 설명

hIFNGR1(NM-HU-190076) was crossed with hIFNGR2(NM-HU-215010) to generate hIFNGR1/hIFNGR2 mice.

검증 데이터

image.png

Fig1. Detection of IFNGR1 expression in colon by RT-PCR. 

Wild type: only one band at 405 bp with primers F1/R1(mIfngr1);

Homozygous: only one band at 461 bp with primers F2/R2(hIFNGR1);


Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig2. Detection of IFNGR2 expression in small intestine by RT-PCR. 

Wild type: only one band at 286 bp with primers F1/R1(mIfngr2);

Homozygous: only one band at 418 bp with primers F2/R2(hIFNGR2);


Abbr. M, DNA marker; HO, homozygous;  WT, wild type.


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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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