hCSF1/hCSF1R(BALB/c)
모델명
BALB/cAnSmoc-Csf1tm2(CSF1)Csf1rem3(hCSF1R)/Smoc
카탈로그
NM-HU-220016
모델 상태
Repository Live
유전자 요약
Official Symbol
CSF1
Official Symbol
CSF1R
모델 설명
검증 데이터
Fig.1 Detection of CSF1 expression in spleen and lung by RT-PCR.
Wild type: only one band at 299 bp with primers F1/R1(mCsf1);
Homozygous: only one band at 261 bp with primers F2/R2(hCSF1);
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of CSF1R expression in spleen and lung by RT-PCR.
Wild type: only one band at 233 bp with primers F1/R1(mCsf1r);
Homozygous: only one band at 345 bp with primers F2/R2(hCSF1R);
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.3 Detection of hCSF1 expression in serum by ELISA (n=3).
Abbr. HO, homozygous; WT, wild type.
Note. hCSF1/hCSF1R and BALB/c mice were i.p. injected with LPS for 6h.
Fig.4 Expression characterization of hCSF1R on Monocytes/ macrophages in Bone marrow in hCSF1/hCSF1R dKI mice.
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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