Cd8a-2A-tdTomato-2A-Luc

모델명

C57BL/6Smoc-Cd8aem(T2A-tdTomato-P2A-Luciferase)1Smoc

카탈로그

NM-KI-225025

모델 상태

Repository Live

PDF 받기

유전자 요약

Official Symbol
Cd8a

모델 설명

T2A-tdTomato-P2A-Luciferase expression cassette was knocked into the Cd8a gene .
신청분야:Reporter mouse

검증 데이터

Fig.1.png

Fig.1 IVIS automatic exposure. According to the imaging process, the mice were injected with D-Luciferin, and the abdomen, back, and flanks were imaged in vivo. 

image.png

Fig.2 IVIS automatic exposure: ex vivo. According to the imaging process, D-Luciferin was injected, and the mouse brain, heart, lung, kidney, liver,  spleen, thymus, inguinal lymph node, axial lymph node (Axial LN), muscle, and the entire digestive system  (stomach to colon) were taken for imaging.

Fig.3.pngFig.3 Detection of tdTomato in mice thymus by FACS.

Fig.4.png

Fig.4 Detection of tdTomato in mice axillary lymph by FACS.

Fig.5.png

Fig.5 Detection of tdTomato in mice inguinal lymph by FACS.

Fig.6.pngFig.6 Detection of tdTomato in mice spleen by FACS.

Fig.7.pngFig.7 Detection of tdTomato in mice PB by FACS.

*The validation data above were completed in cooperation with Crownbio.


당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

조회
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

조회