hCD40(BALB/c)

모델명

BALB/cAnSmoc-Cd40em1(hCD40)/Smoc

카탈로그

NM-HU-2000047

모델 상태

Embryo cryopreservation

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유전자 요약

Official Symbol
CD40

Synonyms

IGM; p50; Bp50; GP39; IMD3; TRAP; HIGM1; T-BAM; Tnfrsf5; AI326936

NCBI ID

21939

MGI ID

88336

Ensembl ID

ENSMUSG00000017652

Pubmed

CD40

Human Ortholog

CD40

모델 설명

The endogenous mouse Cd40 gene was replaced by human CD40 gene.
신청분야：Immunotherapy,drug screening

검증 데이터

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Fig1. Analysis of hCD40 expression in PBMC in the hCD40 mice by FACS. hCD40 was expressed on B cells in PB.

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Fig2. Analysis of hCD40 expression on splenic B cells by FACS. hCD40 was expressed on the B cells in the spleen.

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Fig3. Analysis of human CD40 expression on splenic DCs and macrophages by FACS . The homozygous KI mouse expresses human CD40 on DCs and macrophages.（Provided by CrownBio）


당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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