hIL12A
모델명
C57BL/6Smoc-Il12atm3(hIL12A)/Smoc
카탈로그
NM-HU-2000056
모델 상태
Embryo cryopreservation
유전자 요약
Official Symbol
Il12a
모델 설명
The endogenous mouse Il12a gene was replaced by human IL12A gene.
검증 데이터
Fig1. Detection of IL12A expression in spleen by RT-PCR.
Wild type: only one band at 198 bp with primers F1/R1(mIl12a);
Homozygous: only one band at 488 bp with primers F2/R2(hIL12A);
Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig2. Detection of human IL12P70 and mouse IL12P70 expression in serum by ELISA (n=3).
Abbr. HO, homozygous; WT, wild type.
Note. hIL12A/hIL12B and C57BL/6 mice were i.p. injected with LPS for 2h.
당신은 또한 좋아할 수 있습니다
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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