Arc-CreERT2
모델명
C57BL/6Smoc-Arcem1(CreERT2-SV40-pA)Smoc
카탈로그
NM-KI-200101
모델 상태
Embryo cryopreservation
유전자 요약
Official Symbol
Arc
모델 설명
검증 데이터
Fig.1 Detection of tdTomato (red) in the brain of ArcCreERT2/+; Rosa26tdTomato/+ mouse after tamoxifen treatment. CreERT2-mediated recombination in the brain can be induced by tamoxifen. Some leakiness were detected in the hippocampus and thalamus prior to tamoxifen exposure.
Fig. 2 Detection of tdTomato (red) in various tissues of ArcCreERT2/+; Rosa26tdTomato/+ mice. CreERT2-mediated recombination in the brain, liver, kidney, pancreas, lung, stomach, submandibular gland, skin, testis and epididymis, pituitary gland and eye can be induced by tamoxifen. Some leakiness were detected in the brain and brown fat prior to tamoxifen exposure. (For more detailed information please contact our technical advisor.)
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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