hHLA-A11

모델명

C57BL/6Smoc-H2-K1em1(hHLA-A11)Smoc

카탈로그

NM-HU-204987

모델 상태

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유전자 요약

Official Symbol
H2-K1

Synonyms

K-f; H-2K; H2-K; H2-D1; H2-K_p; H-2K(d)

NCBI ID

14972

MGI ID

95904

Ensembl ID

ENSMUSG00000061232

Pubmed

H2-K1

Human Ortholog

HLA-A，HLA-E，HLA-F

모델 설명

The endogenous mice H2-K1 gene was replaced by human HLA-A11 gene.

검증 데이터

image.png

Fig1. Detection of HLA-A11 expression in liver and spleen by RT-PCR.

Wild type: only one band at 369 bp with primers F1/R1(mH2-k1);

Heterozygous: one band at 369 bp with primers F1/R1(mH2-k1) and one band at 215 bp with primers F2/R2(hHLA-A11).

Abbr. M, DNA marker; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of HLA-A11 expression in blood in HLA-A11 KI mice.

당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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