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Models

About 42,531 results
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hTNFRSF10B

모델명：C57BL/6Smoc-Tnfrsf10bem1(hTNFRSF10B)/Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-210005

The endogenous mice Tnfrsf10B gene was replaced by human TNFRSF10B gene

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hIL2/hIL2RA/hIL2RB/hIL2RG

모델명：C57BL/6Smoc-Il2tm3(hIL2)Il2ratm1(hIL2RA)Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-210415

hIL2/hIL2RA(NM-HU-200275) was crossed with hIL2RA/hIL2RB/hIL2RG(NM-HU-210414) to generate hIL2/hIL2RA/hIL2RB/hIL2RG mice.

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hMERTK

모델명：C57BL/6Smoc-Mertkem1(hMERTK)/Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-2000031

The endogenous mouse Mertk gene was replaced by human MERTK gene.

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Zbtb46-IRES-Cre

모델명：C57BL/6Smoc-Zbtb46em1(IRES-iCre)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-200096

A  IRES-iCre expression cassette was knocked into the Zbtb46 gene stop codon site. This strain carries a significant risk of reproductive system leakage. Avoid using homozygotes and female Cre mice. It is recommended to use male mice, as they have a lower probability of leakage. After mating, offspring should be genotyped and promptly checked for any occurrence of reproductive leakage.

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hPD-1/hCTLA-4

모델명：C57BL/6Smoc-Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-00079

hPD-1(NM-HU-00015) was crossed with hCTLA4(NM-HU-00014)to generate hPD-1/hCTLA4 mice

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Foxp3-V5-AviTag-IRES-Luc-2A-tdTomato

모델명：C57BL/6Smoc-Foxp3em1(V5-AviTag-IRES-luci-2A-tdTomato)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-18034

A V5-AviTag-IRES-luci-2A-tdTomato expression cassette was inserted before the stop codon TGA of mouse Foxp3 gene to establish a multi-labeled knockin model with V5, Avi, luciferase and tdTomato fluorescent protein.

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Calca-Cre

모델명：C57BL/6Smoc-Calcaem1(iCre-2A)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-200302

iCre-2A expression cassette was knocked into the Calca gene start codon site.

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hGPR75

모델명：C57BL/6Smoc-Gpr75em1(hGPR75)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-215056

The endogenous mouse Gpr75 gene was replaced by human GPR75 gene.

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hCTLA-4/4-1BB

모델명：C57BL/6Smoc-Ctla4em1(hCTLA4) Tnfrsf9em1(hTNFRSF9) /Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-18020

This CTLA4 and 4-1BB double knockin strain is established by crossing CTLA4-HU and 4-1BB-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

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Il18-Luc-2A-EGFP

모델명：C57BL/6Smoc-Il18em1(Luc-eGFP)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-00032

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il18.

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