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Models

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Avp-IRES-Cre

모델명：C57BL/6Smoc-Avpem1(IRES2-Cre-WPRE-polyA)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-200142

A IRES2-Cre-WPRE-polyA expression cassette was knocked into the Avp gene stop codon site. Avp encodes arginine vasopressin. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying hypertension.

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hPD-L1(2)/hCD28

모델명：C57BL/6Smoc-Cd274em2(hPD-L1)Cd28em2(hCD28)/Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-210370

hPD-L1(2)(NM-HU-190039) was crossed with hCD28(NM-HU-190011）to generate hPD-L1(2)/hCD28 mice

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Slc17a6-CreERT2

모델명：C57BL/6Smoc-Slc17a6em2(CreERT2)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-190011

This tamoxifen-inducible Slc17a6-CreERT2 tool mouse model was established by inserting a 2A-CreERT2-WPRE-polyA co-expression cassette into the stop codon of Slc17a6 gene.

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hFCGRT(NMG）

모델명：NOD-PrkdcscidIl2rgem1Fcgrtem2(FCGRT)Smoc
모델 상태：Repository Live | 카탈로그：NM-NSG-020

The background of this strain is NMG, and its endogenous Fcgrt gene is replaced with human FCGRT.

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Casp8-Flox

모델명：C57BL/6Smoc-Casp8em1(flox)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-CKO-190003

These Casp8 flox mice possess loxP sites flanking exons 4. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

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Aldh7A1-KO

모델명：C57BL/6Smoc-Aldh7A1em1Smoc
모델 상태：Developing | 카탈로그：TBD

Exon 2-5 of Aldh7A1 gene was deleted to generate Aldh7A1 knockout mice.

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Col1a2-2A-DreERT2

모델명：C57BL/6Smoc-Col1a2em1(2A-DreERT2-Wpre-pA)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-210109

2A-DreERT2-Wpre-pA expression cassette was knocked into the Col1a2 gene .

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Axin2-2A-DreERT2

모델명：C57BL/6Smoc-Axin2em1(P2A-DreERT2)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-200196

A P2A-DreERT2 expression cassette was knocked into the Axin2 gene stop codon site.

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Tmem119-2A-DTRGFP

모델명：C57BL/6Smoc-Tmem119em4(P2A-DTRGFP)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-200235

A P2A-DTRGFP expression cassette was knocked into the Tmem119 gene stop codon site.

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1300017j02Rik-KO

모델명：C57BL/6Smoc-1300017j02Rikem1Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KO-190231

This 1300017j02Rik knockout mouse model was generated by knocking out the exon2-12 region of the 1300017j02Rik.

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