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Models

About 42,575 results
마우스

Abcb8-Flox

모델명：C57BL/6Smoc-Abcb8em1(flox)Smoc
모델 상태：Developing | 카탈로그：TBD
검증 데이터：아니요

These mice carry loxP sites flanking target exons of Abcb8 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Abcb8 gene.

마우스

hIL2

모델명：C57BL/6Smoc-Il2tm3(hIL2)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-190048
검증 데이터：예

The endogenous mouse Il2 gene was replaced by human IL2 gene.

마우스

Bmal1-Flox

모델명：C57BL/6Smoc-Bmal1em1(flox)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-CKO-200063
검증 데이터：아니요

These mice carry loxP sites flanking exon 8 of Bmal1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Bmal1 gene.

마우스

R26-CreERT2

모델명：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-200041
검증 데이터：예

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA cassette in the Rosa26 locus generated by homologous recombination. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in multiple tissues after tamoxifen treatment.

마우스

hSERPINC1

모델명：C57BL/6Smoc-Serpinc1tm1(hSERPINC1)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-225075
검증 데이터：예

The endogenous mouse Serpinc1 gene was replaced by human SERPINC1 gene.

마우스

Nphs2-CreERT2

모델명：C57BL/6Smoc-Nphs2tm1(IRES-CreERT2)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-00128
검증 데이터：예

An IRES-CreERT2 co-expression cassette is inserted into 3'UTR region of Nphs2 gene via homologous recombination to establish a tamoxifen inducible Nphs2-CreERT2 tool stain.

마우스

MHC Class II(I-A/I-E)-KO(Nod-Scid)

모델명：NOD-PrkdcscidH2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-psem1Smoc
모델 상태：Developing | 카탈로그：NM-KO-18057
검증 데이터：아니요

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the Nod-Scid genetic background and lacked cell surface expression of both class II-A and class II-E MHC proteins.

마우스

C57BL/6

모델명：C57BL/6Smoc
모델 상태：Repository Live | 카탈로그：SM-001
검증 데이터：예

C57BL/6 mice have a high reproductive capacity, a long life span, and a low tumor susceptibility. Male mice are aggressive and fight frequently. Diet can cause obesity, type II diabetes, and atherosclerosis in these mice. The C57BL/6 mouse is the first to have its entire genome sequenced. It is the most extensively used inbred mouse strain as a genetic basis for congenic and mutant mice. It is also used in genetics, metabolism, immunology, neurology, behavioral research, pharmacodynamics, and medication safety evaluation.

마우스

hPD-L1/hSIGLEC15

모델명：C57BL/6Smoc-Cd274em1(hCD274)Siglec15em1(hSIGLEC15)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-2000103
검증 데이터：아니요

hPD-L1(NM-HU-00062) was crossed with hSIGLEC15(NM-HU-190037) to generate hPD-L1/hSIGLEC15.

마우스

hIL1RAP

모델명：C57BL/6Smoc-Il1raptm3(hIL1RAP)/Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-HU-2000070
검증 데이터：예

The endogenous mouse Il1rap gene was replaced by human IL1RAP gene.

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