Sftpc-IRES-CreERT2

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C57BL/6Smoc-Sftpcem(IRES-CreERT2)Smoc

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NM-KI-18020

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Sftpc

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An IRES-CreERT2 co-expression cassette is inserted into 3'UTR region of Sftpc gene  via homologous recombination to establish a tamoxifen inducible Sftpc-CreERT2 tool stain. *This strain CreERT2 has leakage (see validation data for details), please select according to the purpose of the study。

신청분야:Cre recombinase tool

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Fig1. Cre mediated recombination in lung of SftpcCreERT2/+;Rosa26tdTomato/+ mouse.

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Fig2. Detection of tdTomato(red) in various tissues of SftpcCreERT2/+;Rosa26tdTomato/+ mouse. Expression tissues include: lung epithelial cells, testis interstitial cells, salivary glands, muscles. Tissues that unexpressed include brain, spinal cord, retina, heart, liver, brown fat, thymus, kidney, pancreas, large and small intestine, spleen, and skin.(2-months old, male) (For more detailed information please contact our technical advisor.) 


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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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