1. 홈페이지
  2. Models
  3. U-GEMMs
  4. Disease Mice

Models

Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

마우스
Jakmip1-KO
모델명：C57BL/6JSmo-Jakmip1em1Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KO-200995
Disease Connection：autism spectrum disorder
마우스
Kdm3A-KO
모델명：C57BL/6Smoc-Kdm3Aem1Smoc
모델 상태：Developing | 카탈로그：TBD
Disease Connection：obesity
마우스
kif18A-KO
모델명：B6;129S-kif18Atm1Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KO-00008
신청분야：male infertility，orchiatrophy，azoospermia
마우스
Kmt2b-Flox
모델명：C57BL/6JSmo-Kmt2btm1(flox)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-CKO-190029
신청분야：Epigenetic
마우스
KPC
모델명：C57BL/6JSmo-Trp53em4(R172H)Krasem4(LSL-G12D)Tg(Pdx1-cre)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-210096
Disease Connection：pancreatic carcinoma
마우스
KPC(2)
모델명：C57BL/6JSmo-Trp53tm7(R270H-flox)Krasem4(LSL-G12D)Tg(Pdx1-cre)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-220014
Disease Connection：pancreatic carcinoma
마우스
KPC(3)
모델명：C57BL/6JSmo-Krasem4(LSL-G12D)Trp53tm(LSL-R172H)Tg(Pdx1-Cre)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-234804
마우스
Kras-LSL-G12D
모델명：C57BL/6JSmo-Krasem4(LSL-G12D)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-190003
Disease Connection：squamous cell carcinoma, prostate cancer, pancreatic carcinoma, neurofibromatosis, pancreatic ductal adenocarcinoma, juvenile myelomonocytic leukemia, urinary bladder cancer, ovarian cancer
마우스
Lat-Y136F
모델명：C57BL/6JSmo-Latem1(Y136F）Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-200249
Disease Connection：IgG4-related disease
마우스
Ldb3-Flox
모델명：C57BL/6JSmo-Ldb3em1(flox)Smoc
모델 상태：Developing | 카탈로그：NM-CKO-253977
Disease Connection：dilated cardiomyopathy 1C
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