1. 홈페이지
  2. Models
  3. U-GEMMs
  4. Standard GEMMs
  5. Humanized Knockins

Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

마우스
Avil-LSL-hM3Dq-mCherry
모델명：C57BL/6JSmo-Avilem1(LSL-Kozak-hM3Dq-mCherry-WPRE-pA)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-232881
마우스
CAG-hACE2-IRES-Luc-Tg
모델명：C57BL/6JSmo-Tgtn(CAG-human ACE2-IRES-Luciferase-WPRE-polyA)Smoc
모델 상태：Repository Live | 카탈로그：NM-TG-200002
신청분야：corona virus related research
마우스
CMV-hIL34-Tg(NMG)
모델명：NOD.Cg-PrkdcscidIl2rgem1Tg(pCMV-hIL34-pA)1Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-TG-220433
마우스
H11-CAG-LSL-hACHE
모델명：C57BL/6JSmo-Igs2tm1(CAG-LSL-ACHE-WPRE-pA)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-00067
신청분야：Cholinesterase related drug research
마우스
H11-CAG-LSL-hHTTQ148-hHTT 3'UTR
모델명：C57BL/6JSmo-Igs2tm1(CAG-loxP-STOP-loxP-hHTTQ148-hHTT 3'UTR-pA)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-234493
마우스
H11-CAG-LSL-hLILRB4-IRES-EGFP
모델명：C57BL/6JSmo-Igs2tm1(CAG-loxP-STOP-loxP-hLILRB4-IRES-EGFP-WPRE-pA)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-230387
마우스
H11-CAG-LSL-hPSEN1-IRES-tdTomato
모델명：C57BL/6JSmo-Igs2tm1(CAG-LSL-PSEN1-IRES-tdTomato-WPRE-polyA)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-190110
신청분야：Alzheimer's research
마우스
H11-CAG-LSL-LSL-hMYCN-IRES-EGFP
모델명：C57BL/6JSmo-Igs2tm1(CAG-loxp-Neo-Stop-loxp-lox2272-Neo-Stop-lox2272-HA tag-NMYC-IRES-EFGP-WPRE-polyA)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-210145
신청분야：Cancer research
마우스
H11-pAlb-hALB-IRES-Luc
모델명：C57BL/6JSmo-Igs2tm1(ALB promoter-human ALB-IRES-Luciferase-polyA)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-200322
마우스
H11-pAlb-hBAFF
모델명：C57BL/6JSmo-Igs2tm1(pAlb-hBAFF-pA)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-232137
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