1. 홈페이지
  2. Models
  3. U-GEMMs
  4. Standard GEMMs
  5. Humanized Knockins

Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

마우스
R26-pVillin1-hCYP3A4-IRES-tdTomato(FVB)
모델명：FVB-Gt(ROSA)26Sortm1(Gut-CYP3A4-IRES-tdTomato)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-18033
신청분야：metabolism
마우스
R26-SA-LSL-hMycRTG3-ERT2-IRES-EGFP
모델명：C57BL/6JSmo-Gt(ROSA)26Sortm1(SA-loxp-stop-loxp-hMycRTG3-ERT2-IRES-EGFP-WPRE-pA)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-225096
마우스
Rab31-hRAB31*Y76F/Y86F/Y137F
모델명：C57BL/6JSmo-Rab31tm1(hRAB31*Y76F/Y86F/Y137F)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-210419
마우스
Rag2-KO/hHER2
모델명：C57BL/6JSmo-Rag2em2Erbb2tm1(hHER2)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-234873
마우스
Rag2-KO/hTROP2
모델명：C57BL/6JSmo-Rag2em2Tacstd2tm(hTACSTD2)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-234872
마우스
Rag2-KO/hVEGFR2
모델명：C57BL/6JSmo-Rag2em1Kdrtm2(hKDR)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-200280
마우스
Rag2/IL2rg-KO/hCD40
모델명：C57BL/6JSmo-Cd40tm1(hCD40)Rag2em1Il2rgem1Smoc
모델 상태：Developing | 카탈로그：NM-HU-2000112
신청분야：Immunotherapy,cancer research,drug screening
마우스
Rag2/Il2rg-KO/hCSF1/hCSF2/hIL3
모델명：C57BL/6JSmo-Rag2emIl2rgemIl3tm1(hIL3)Csf2tm1(CSF2)Csf1tm2(CSF1)Smoc
모델 상태：Repository Live | 카탈로그：NM-XA-234932
마우스
Rag2/Il2rg-KO/hCSF1/hCSF2/hIL3/hSIRPA(2)/hTHPO
모델명：C57BL/6JSmo-Rag2emIl2rgemIl3tm1(hIL3)Csf2tm1(CSF2)Csf1tm2(CSF1)Thpotm1(hTHPO)Sirpatm2(hSIRPA)Smoc
모델 상태：Repository Live | 카탈로그：NM-XA-234933
마우스
Rag2/IL2rg-KO/hSIRPA(2)/hCD47
모델명：C57BL/6JSmo-Rag2em1Il2rgem1Sirpatm1(hSIRPA)Cd47tm1(hCD47)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-2000019
신청분야：Immunotherapy,drug screening
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