1. 홈페이지
  2. Models
  3. U-GEMMs
  4. Disease Mice

Models

Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

마우스
Ptger4-Flox
모델명：C57BL/6JSmo-Ptger4em1(flox)Smoc
모델 상태：Repository Live | 카탈로그：NM-CKO-2100609
Disease Connection：dilated cardiomyopathy
마우스
pThy1-MAPT-P301L(tauP301L)-Tg(V1)
모델명：C57BL/6JSmo-Tgtn(pThy1-MAPT-P301L(tauP301L))1Smoc
모델 상태：Developing | 카탈로그：NM-KI-235095
마우스
pThy1-MAPT-P301L(tauP301L)-Tg(V2)
모델명：C57BL/6JSmo-Tgtn(pThy1-MAPT-P301L(tauP301L))2Smoc
모델 상태：Developing | 카탈로그：NM-KI-235096
마우스
Ptpn11-Flox
모델명：C57BL/6JSmo-Ptpn11em1(flox)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-CKO-231881
Disease Connection：juvenile myelomonocytic leukemia, Noonan syndrome 1, disease of metabolism
마우스
Pts-KO
모델명：C57BL/6JSmo-Ptsem1Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KO-200641
Disease Connection：BH4-deficient hyperphenylalaninemia A
마우스
R26-CAG-loxp-tdTomato-loxp2272-Tag-IRES-EGFP-2A-Luc-loxp-loxp2272
모델명：C57BL/6JSmo-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-loxp-tdTomato-polyA-loxp2272-polyA-Wpre-Tag-IRES-EGFP-2A-Luciferase-loxp-loxp2272)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-200033
신청분야：Spontaneous tumor model
마우스
R26-CAG-LSL-AAVR
모델명：C57BL/6JSmo-Gt(ROSA)26Sorem(SA-FRT-2XpA-CAG-FRT-LSL-AAVR-WPRE-polyA)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-190099
신청분야：Dyslexia related
마우스
R26-CAG-LSL-hACE2-IRES-tdTomato
모델명：C57BL/6JSmo-Gt(ROSA)26Sortm1(SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyA)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-200188
신청분야：corona virus related research
마우스
R26-CAG-LSL-hBCR/ABL
모델명：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-loxp-STOP-loxp-BCR-ABL-IRES-Luciferase-2A-tdTomato-WPRE-polyA)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-190127
신청분야：Chronic Myelocytic Leukemia(CML) research
마우스
R26-CAG-LSL-hEGFR*L858R/T790M-IRES-Luc-2A-tdTomato
모델명：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-EGFR (L858R-T790M)-IRES-luciferase-2A-tdTomato)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-190068
신청분야：cancer research
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