1. 홈페이지
  2. Models
  3. U-GEMMs
  4. Disease Mice

Models

Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

마우스
Tigre-pTRE-MAPT-P301L-CAG-LSL-tTA
모델명：C57BL/6JSmo-Igs7em1(2xIns-pTRE-MAPT-P301L-WPRE-pA-2xIns-CAG-LSL-tTA-WPRE-pA)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-235089
마우스
Tmem173-V154M
모델명：C57BL/6JSmo-Tmem173em(V154M)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-225039
신청분야：STING-associated vasculopathy with onset in infancy (SAVI)
마우스
Tnf-KO
모델명：C57BL/6JSmo-Tnfem1Smoc
모델 상태：Repository Live | 카탈로그：NM-KO-00100
Disease Connection：rheumatoid arthritis, spondyloarthropathy
마우스
Tnf-KO(3)
모델명：C57BL/6JSmo-Tnfem2Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KO-232670
마우스
Trp53-Flox
모델명：C57BL/6JSmo-Trp53tm2(flox)Smoc
모델 상태：Repository Live | 카탈로그：NM-CKO-18005
Disease Connection：medulloblastoma, breast cancer, prostate cancer, central nervous system cancer, osteosarcoma, pancreatic carcinoma, malignant astrocytoma, thyroid gland carcinoma, ovarian cancer, urinary bladder cancer, alveolar rhabdomyosarcoma, glioblastoma, pancreatic ductal adenocarcinoma, squamous cell carcinoma, thyroid gland cancer, CHARGE syndrome, stomach cancer, invasive lobular carcinoma, endometrial cancer, hereditary breast ovarian cancer syndrome, pancreatic mucinous cystadenoma
마우스
Trp53-KO(2)
모델명：C57BL/6JSmo-Trp53em5Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KO-191203
Disease Connection：medulloblastoma, malignant astrocytoma, neurofibromatosis, diffuse large B-cell lymphoma, Li-Fraumeni syndrome
마우스
Trp53-LSL-R172H
모델명：C57BL/6JSmo-Trp53tm(LSL- R172H)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-220071
신청분야：Spontaneous Tumor
마우스
Trp53inp1-KO
모델명：C57BL/6JSmo-Trp53inp1em1Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KO-201224
Disease Connection：abdominal obesity-metabolic syndrome 1
마우스
Trpv4-Flox
모델명：C57BL/6JSmo-Trpv4em1(flox)Smoc
모델 상태：Repository Live | 카탈로그：NM-CKO-2103058
마우스
Trpv4-KO
모델명：C57BL/6JSmo-Trpv4em1Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KO-225019
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