1. 홈페이지
  2. Models
  3. U-GEMMs
  4. Disease Mice
  5. Rare Disease

Models

Rare Disease

Rare diseases are those that affect only a small percentage of the world’s population. Most rare diseases are genetic. We provide many gene-engineered mouse models which are helpful for new therapies exploration and orphan drug development.

마우스
Ppm1k-KO
모델명：C57BL/6JSmo-Ppm1kem1Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KO-201326
Disease Connection：maple syrup urine disease
마우스
Prf1-KO
모델명：C57BL/6JSmo-Prf1em1Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KO-190193
신청분야：Immune-related
마우스
Prkn-KO
모델명：C57BL/6JSmo-Prknem1Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KO-190335
Disease Connection：Parkinson's disease 2
마우스
Ptpn11-Flox
모델명：C57BL/6JSmo-Ptpn11em1(flox)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-CKO-231881
Disease Connection：juvenile myelomonocytic leukemia, Noonan syndrome 1, disease of metabolism
마우스
Pts-KO
모델명：C57BL/6JSmo-Ptsem1Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KO-200641
Disease Connection：BH4-deficient hyperphenylalaninemia A
마우스
R26-CAG-LSL-hPIK3CA*H1047R-IRES-Luc-2A-tdTomato
모델명：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-190065
Disease Connection：breast cancer, CLOVES syndrome, ovarian cancer, brain glioma
마우스
R26-CAG-LSL-hSOD1*G94A-IRES-EGFP
모델명：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-FRT-LSL- SOD1(G94A)-IRES-EGFP-WPRE-pA)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-200263
Disease Connection：amyotrophic lateral sclerosis type 1
마우스
R26-SA-Loxp-PGK-Neo-Loxp-Pik3ca-H1047R
모델명：C57BL/6JSmo-Gt(ROSA)26Sorem1(SA-Loxp-PGK-Neo-pA-Loxp-Pik3ca-H1047R-pA)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-225095
마우스
Raf1-D486N
모델명：C57BL/6JSmo-Raf1em1(D486N)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-200252
신청분야：Noonan syndrome
마우스
Rag1-KO(Rag1-EGFP)
모델명：B6.129S-Rag1tm1(loxP-EGFP-PolyA-loxP-Neo-loxP)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-00069
신청분야：Immunodeficiency,tumor-bearing model
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