Immune Checkpoints

SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice. 

마우스
모델명:C57BL/6JSmo-Ctla4tm1(hCTLA4)Cd274tm1(hPD-L1)Smoc
모델 상태:Embryo cryopreservation | 카탈로그:NM-HU-00102
신청분야:Immunotherapy,cancer research,drug screening
마우스
모델명:C57BL/6JSmo-Cd274tm1(hPD-L1)Lag3tm1(hLAG3)Smoc
모델 상태:Embryo cryopreservation | 카탈로그:NM-HU-00137
신청분야:Immunotherapy,cancer research,drug screening
마우스
모델명:C57BL/6JSmo-Cd274tm1(hPD-L1)Tnfrsf4tm1(hTNFRSF4)Smoc
모델 상태:Embryo cryopreservation | 카탈로그:NM-HU-00111
신청분야:cancer research,Immunotherapy,drug screening
마우스
모델명:C57BL/6JSmo-Cd274tm1(hCD274)Siglec15tm1(hSIGLEC15)Smoc
모델 상태:Embryo cryopreservation | 카탈로그:NM-HU-2000103
신청분야:Immunotherapy,cancer research,drug screening
마우스
모델명:C57BL/6JSmo-Sirpatm2(hSIRPA)Cd274tm1(hCD274)Smoc
모델 상태:Embryo cryopreservation | 카탈로그:NM-HU-2000099
신청분야:Immunotherapy,cancer research,drug screening
마우스
모델명:C57BL/6JSmo-Tmem173tm1(hTMem173)Cd274tm1(hCD274)Smoc
모델 상태:Embryo cryopreservation | 카탈로그:NM-HU-2000105
신청분야:Immunotherapy,cancer research,drug screening
마우스
모델명:C57BL/6JSmo-Cd274tm1(hPD-L1)Tigittm1(hTIGIT)Smoc
모델 상태:Embryo cryopreservation | 카탈로그:NM-HU-18013
신청분야:Immunotherapy,cancer research,drug screening
마우스
모델명:C57BL/6JSmo-Cd274tm1(hPD-L1)Havcr2tm1(hHAVCR2)Smoc
모델 상태:Embryo cryopreservation | 카탈로그:NM-HU-190056
신청분야:Immunotherapy,cancer research,drug screening
마우스
모델명:C57BL/6JSmo-Visrtm1(hVSIR)Cd274tm1(hCD274)Smoc
모델 상태:Embryo cryopreservation | 카탈로그:NM-HU-2000094
신청분야:Immunotherapy,cancer research,drug screening
마우스
모델명:C57BL/6JSmo-Selplgtm1(hSELPLG)Smoc
모델 상태:Embryo cryopreservation | 카탈로그:NM-HU-00046
신청분야:Immunotherapy,cancer research,drug screening
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