1. 홈페이지
  2. Models
  3. U-GEMMs
  4. Standard GEMMs
  5. Humanized Knockins

Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

마우스
hCD47(Balb/c,2)
모델명：BALB/cJSmo-Cd47tm2(hCD47)/Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-210359
신청분야：inmmue therapy；drug screening
마우스
hCD47/hCSF2/hIL3/hSIRPA(2)
모델명：C57BL/6JSmo-Il3tm1(hIL3)Csf2tm1(CSF2)Sirpatm2(hSIRPA)Cd47tm1(hCD47)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-200270
마우스
hCD47/hCTLA-4/hSIRPA(2)
모델명：C57BL/6JSmo-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Ctla4tm1(hCTLA4) Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-210368
신청분야：inmmue therapy;drug screening
마우스
hCD47/hPD-1/hPD-L1(2)/hSIRPA(2)
모델명：C57BL/6JSmo-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Pdcd1tm1(hPDCD1)Cd274tm2(hPD-L1)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-220029
마우스
hCD47/hPD-1/hPD-L1/hSIRPA(2)
모델명：C57BL/6JSmo-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-210358
신청분야：inmmue therapy；drug screening
마우스
hCD47/hPD-1/hPD-L1/hSIRPA(2)(BALB/c)
모델명：BALB/cJSmo-Pdcd1tm(hPDCD1)Cd274tm(hPD-L1)Sirpatm4(hSIRPA)Cd47tm1(hCD47)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-220143
마우스
hCD47/hPD-1/hSIRPA(2)
모델명：C57BL/6JSmo-Sirpatm2(hSIRPA)Cd47tm1(hCD47) Pdcd1tm1(hPDCD1)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-HU-2000090
신청분야：Immune-related
마우스
hCD47/hPD-L1/hSIRPA(2)
모델명：C57BL/6JSmo-Sirpatm2(hSIRPA)Cd274tm1(hCD274)Cd47tm1(hCD47)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-2000095
신청분야：Immunotherapy,cancer research,drug screening
마우스
hCD47/hSIRPA(2)
모델명：C57BL/6JSmo-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-2000111
신청분야：Immunotherapy,cancer research,drug screening
마우스
hCD47/hSIRPA(2)(BALB/c)
모델명：BALB/cJSmo-Sirpatm4(hSIRPA)SmocCd47tm1(hCD47)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-210020
신청분야：tumor research；inmmue therapy；drug screening
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