1. 홈페이지
  2. Models
  3. U-GEMMs
  4. Standard GEMMs
  5. Humanized Knockins

Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

마우스
hFCGR2B
모델명：C57BL/6JSmo-Fcgr2btm3(hFCGR2B)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-2000010
신청분야：Immunotherapy,cancer research,drug screening
마우스
hFCGR2B/h4-1BB(2)
모델명：C57BL/6JSmo-Fcgr2btm2(FCGR2B)Tnfrsf9tm2(TNFRSF9)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-210352
신청분야：inmmue therapy；drug screening
마우스
hFCGR2B/hCD40
모델명：C57BL/6JSmo-Fcgr2Btm1(hFCGR2B)Cd40tm1(hCD40)/Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-200262
마우스
hFCGR2B/hOX40
모델명：C57BL/6JSmo-Fcgrt2Btm2(hFCGRT2B)Tnfrsf4tm1(hTNFRSF4)/Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-200265
마우스
hFCRN
모델명：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-hFcRn)Fcgrtem1Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-00109
신청분야：cancer research,Immunotherapy,drug screening
마우스
hFCRN(2)
모델명：C57BL/6JSmo-Fcgrttm2(hFCGRT)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-190070
신청분야：Immunotherapy,cancer research,drug screening
마우스
hFCRN(3)
모델명：C57BL/6JSmo-Fcgrttm3(hFCGRT)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-2000032
신청분야：Immunotherapy,drug screening
마우스
hFCRN(NMG)
모델명：NOD.Cg-PrkdcscidIl2rgem1Fcgrttm2(FCGRT)Smoc
모델 상태：Repository Live | 카탈로그：NM-NSG-020
신청분야：Immunotherapy,cancer research,drug screening
마우스
hFGF21
모델명：C57BL/6JSmo-Fgf21tm1(hFGF21)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-234339
마우스
hFGFR1
모델명：C57BL/6JSmo-Fgfr1tm(hFGFR1)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-230070
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