1. 홈페이지
  2. Models
  3. U-GEMMs
  4. Standard GEMMs
  5. Humanized Knockins

Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

마우스
R26-CAG-LSL-hAR-IRES-EGFP
모델명：C57BL/6JSmo-Gt(ROSA)26Sortm1(R26-CAG-Loxp-Stop-Loxp-hAR-IRES-EGFP-WPRE-pA)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-215053
마우스
R26-CAG-LSL-hBCR/ABL
모델명：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-loxp-STOP-loxp-BCR-ABL-IRES-Luciferase-2A-tdTomato-WPRE-polyA)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-190127
신청분야：Chronic Myelocytic Leukemia(CML) research
마우스
R26-CAG-LSL-hCD2*C truncated
모델명：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-hCD2 C truncated-WPRE-polyA)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-200321
마우스
R26-CAG-LSL-hCD63-copGFP
모델명：C57BL/6JSmo-Gt(ROSA)26Sortm1(pCAG-FRT-loxp-stop-loxp-hCD63-copGFP-6xHis-WPRE-polyA-FRT)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-200044
신청분야：Exosome tracing model
마우스
R26-CAG-LSL-hDSG2
모델명：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-hDSG2-WPRE-pA)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-210444
마우스
R26-CAG-LSL-hEGFR*L858R/T790M-IRES-Luc-2A-tdTomato
모델명：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-EGFR (L858R-T790M)-IRES-luciferase-2A-tdTomato)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-190068
신청분야：cancer research
마우스
R26-CAG-LSL-hEGFR*L858R/T790M/C797S-IRES-Luc-2A-tdTomato
모델명：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-EGFR (L858R-T790M-C797S)-IRES-luciferase-2A-tdTomato)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-190067
신청분야：cancer research
마우스
R26-CAG-LSL-hEGFR*T790M-IRES-Luc-2A-tdTomato
모델명：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-EGFR (T790M) -IRES-Luciferase-2A-tdTomato)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-190070
신청분야：cancer research
마우스
R26-CAG-LSL-hEGFR-IRES-Luc-2A-tdTomato
모델명：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-EGFR-IRES-luciferase-2A-tdTomato)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-190066
신청분야：cancer research
마우스
R26-CAG-LSL-hEGFRvIII-IRES-Luc
모델명：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-Kozak-hEGFRvIII-IRES-Luc-WPRE-pA)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-233898
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