1. 홈페이지
  2. Models
  3. U-GEMMs
  4. Standard GEMMs
  5. Humanized Knockins

Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

마우스
hPD-1/hCD40
모델명：C57BL/6JSmo-Pdcd1tm1(hPDCD1)Cd40tm1(hCD40)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-190017
신청분야：Immune-related
마우스
hPD-1/hCTLA-4
모델명：C57BL/6JSmo-Pdcd1tm1(hPDCD1)Ctla4tm1(hCTLA4)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-00079
신청분야：cancer research,Immunotherapy,drug screening
마우스
hPD-1/hCTLA-4(BALB/c)
모델명：BALB/cJSmo-Pdcd1tm1(hPDCD1)Ctla4tm1(hCTLA4)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-200277
마우스
hPD-1/hICOS(2)
모델명：C57BL/6JSmo-Pdcd1tm1(hPDCD1)Icostm1(hICOS)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-2000100
신청분야：Immunotherapy,cancer research,drug screening
마우스
hPD-1/hIL1B
모델명：C57BL/6JSmo-Pdcd1tm1(hPDCD1)Il1btm3(hIL1B)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-210018
신청분야：tumor research；inmmue therapy；drug screening
마우스
hPD-1/hLAG3
모델명：C57BL/6JSmo-Pdcd1tm1(hPDCD1)Lag3tm1(hLAG3)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-00101
신청분야：Immunotherapy,cancer research,drug screening
마우스
hPD-1/hLAG3/hTIGIT
모델명：C57BL/6JSmo-Pdcd1tm1(hPDCD1)Lag3tm1(hLAG3)Tigittm1(hTIGIT)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-200258
신청분야：tumor research；inmmue therapy；drug screening
마우스
hPD-1/hOX40
모델명：C57BL/6JSmo-Pdcd1tm1(hPDCD1)Tnfrsf4tm3(hTNFRSF4) Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-00108
신청분야：cancer research,Immunotherapy,drug screening
마우스
hPD-1/hPD-L1
모델명：C57BL/6JSmo-Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-00100
신청분야：Immunotherapy,cancer research,drug screening
마우스
hPD-1/hPD-L1(2)/hCCR8
모델명：C57BL/6JSmo-Pdcd1tm1(hPDCD1)Cd274tm2(hPD-L1)Ccr8tm1(hCCR8)/Smoc
모델 상태：Developing | 카탈로그：NM-HU-210402
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