1. 홈페이지
  2. Models
  3. U-GEMMs
  4. Standard GEMMs
  5. Humanized Knockins

Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

마우스
hPD-1/hPD-L1(BALB/c)
모델명：BALB/cJSmo-Pdcd1tm(hPDCD1)Cd274tm(hPD-L1)/Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-220142
마우스
hPD-1/hPD-L1/hCD73(2)
모델명：C57BL/6JSmo-Pdcd1tm1(hPD-1)Cd274tm1(hPD-L1)Nt5etm2(hNT5E)/Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-210410
마우스
hPD-1/hPD-L1/hCTLA-4
모델명：C57BL/6JSmo-Pdcd1tm1(hPD-1)Cd274tm1(hPD-L1)Ctla4tm1(hCTLA4)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-200266
마우스
hPD-1/hPD-L1/hIDO1
모델명：C57BL/6JSmo-Ido1tm1(hIDO1)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-00120
신청분야：cancer research,Immunotherapy,drug screening
마우스
hPD-1/hPD-L1/hLAG3
모델명：C57BL/6JSmo-Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Lag3tm1(hLAG3)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-190028
신청분야：Immune-related
마우스
hPD-1/hPD-L1/hOX40
모델명：C57BL/6JSmo-Tnfrsf4tm3(hTNFRSF4)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-00122
신청분야：Immunotherapy,cancer research,drug screening
마우스
hPD-1/hPD-L1/hPD-L2
모델명：C57BL/6JSmo-Pdcd1lg2tm1(hPDCD1LG2)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)/Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-190060
신청분야：Immunotherapy,cancer research,drug screening
마우스
hPD-1/hPD-L1/hTIGIT
모델명：C57BL/6JSmo-Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Tigittm1(hTIGIT)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-200267
마우스
hPD-1/hPD-L1/hTIM3
모델명：C57BL/6JSmo-Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Havcr2tm1(hHAVCR2)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-200264
마우스
hPD-1/hPVRIG
모델명：C57BL/6JSmo-Pdcd1tm1(hPDCD1)Pvrigtm1(hPVRIG)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-231147
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