1. 홈페이지
  2. Models
  3. U-GEMMs
  4. Standard GEMMs
  5. Point Mutation Knockins

Models

Point Mutation Knockins

Point mutant knockin mouse model is a mouse in which one or more nucleotides are replaced by mutant nucleotides in the genome. This may result in amino acid changes within the protein sequence, and transcription terminated, thereby significantly affecting the normal function of the protein. Point mutation mouse models are widely used to study the role of specific nucleotides or amino acids in genetic elements or proteins, as well as to mimic human genetic diseases.

마우스
Tcf4-A613V
모델명：C57BL/6JSmo-Tcf4em(A613V)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-220388
마우스
Tcf4-G502S/G508S/G518S
모델명：C57BL/6JSmo-Tcf4em(QGQSVSSGSSEIKSDDEGD502-518QSQSVSSSSSEIKSDDESD)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-220595
마우스
Tlr7-Y264H
모델명：C57BL/6JSmo-Tlr7em(Y264H)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-230071
마우스
Tm6sf2-E167K
모델명：C57BL/6JSmo-tm6sf2em1(E167K)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-200002
신청분야：Myocardial infarction and total cholesterol related
마우스
Tmem173-V154M
모델명：C57BL/6JSmo-Tmem173em(V154M)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-225039
신청분야：STING-associated vasculopathy with onset in infancy (SAVI)
마우스
Tnnt2-R158W
모델명：C57BL/6JSmo-Tnnt2em2R158WSmoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-233285
마우스
Tph1-R251X
모델명：C57BL/6JSmo-Tph1em1(R251X)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-232088
마우스
Trap1-K128Q
모델명：C57BL/6JSmo-Trap1em1(K128Q)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-210091
마우스
Trap1-K128R
모델명：C57BL/6JSmo-Trap1em1(K128R)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-210090
마우스
Trap1-K128T
모델명：C57BL/6JSmo-Trap1em1(K128T)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-210089
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