1. 홈페이지
  2. Models
  3. U-GEMMs
  4. Standard GEMMs
  5. Point Mutation Knockins

Models

Point Mutation Knockins

Point mutant knockin mouse model is a mouse in which one or more nucleotides are replaced by mutant nucleotides in the genome. This may result in amino acid changes within the protein sequence, and transcription terminated, thereby significantly affecting the normal function of the protein. Point mutation mouse models are widely used to study the role of specific nucleotides or amino acids in genetic elements or proteins, as well as to mimic human genetic diseases.

마우스
Trpm8-S966A
모델명：C57BL/6JSmo-Trpm8em1(S966A)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-190101
신청분야：Cation channel
마우스
Ttr-G103R
모델명：B6;129S-Ttrtm1(G103R)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-00134
마우스
Vps54-L967Q
모델명：C57BL/6JSmo-Vps54em1(L967Q)/Smoc
모델 상태：Developing | 카탈로그：NM-KI-232086
마우스
Wap-Trp53*R172H-Tg
모델명：C57BL/6JSmo-Tg(Wap-P53(R172H))1Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-TG-220193
마우스
Zap70-W163C(Balb/c)
모델명：BALB/cJSmo-Zap70em(W163C)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-210366
Disease Connection：rheumatoid arthritis
마우스
Zbtb46-T11A
모델명：C57BL/6JSmo-Zbtb46em(T11A)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-215097
마우스
1110025M09Rik-S6x
모델명：C57BL/6JSmo-1110025M09Rikem(S6X)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-215102
마우스
2210010C04Rik-D23A
모델명：C57BL/6JSmo-2210010C04Rikem1D23ASmoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-232248
마우스
9030622O22Rik-c.T376C
모델명：C57BL/6JSmo-9030622O22Rikem1(T-376C)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-200291
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