1. 홈페이지
  2. Models
  3. U-GEMMs
  4. Standard GEMMs
  5. Point Mutation Knockins

Models

Point Mutation Knockins

Point mutant knockin mouse model is a mouse in which one or more nucleotides are replaced by mutant nucleotides in the genome. This may result in amino acid changes within the protein sequence, and transcription terminated, thereby significantly affecting the normal function of the protein. Point mutation mouse models are widely used to study the role of specific nucleotides or amino acids in genetic elements or proteins, as well as to mimic human genetic diseases.

마우스
Nphs2-A286V
모델명：C57BL/6JSmo-Nphs2em1(A286V)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-200278
Disease Connection：hereditary glomerular disease
마우스
Nphs2-R231Q
모델명：C57BL/6JSmo-Nphs2em1(R231Q)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-200277
Disease Connection：hereditary glomerular disease
마우스
Pah-R261Q
모델명：C57BL/6JSmo-Pahem(R261Q)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-225102
마우스
Pah-R408W
모델명：C57BL/6JSmo-Pahem(R408W)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-225103
마우스
Pde6b-R560C (Rd10)
모델명：C57BL/6JSmo-Pde6bem1R560CSmoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-232201
마우스
Pde6b-Y347* (Rd1)
모델명：C57BL/6JSmo-Pde6bem1Y347*Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-232202
마우스
Pgr-2A-Ikbkb*EE
모델명：C57BL/6JSmo-Pgrem(2A-Flag-Ikbkb*S177E/S181E)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-220023
마우스
Plcg2-P522R
모델명：C57BL/6JSmo-Plcg2em(P522R)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-220042
마우스
Pnpla3-I148M
모델명：C57BL/6JSmo-Pnpla3em1(I148M)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-200185
신청분야：Non-alcoholic fatty liver disease
마우스
Ptpn2-Y278C
모델명：C57BL/6JSmo-Ptpn2tm(Y278C)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-225038
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