1. 홈페이지
  2. Models
  3. U-GEMMs
  4. Standard GEMMs
  5. Point Mutation Knockins

Models

Point Mutation Knockins

Point mutant knockin mouse model is a mouse in which one or more nucleotides are replaced by mutant nucleotides in the genome. This may result in amino acid changes within the protein sequence, and transcription terminated, thereby significantly affecting the normal function of the protein. Point mutation mouse models are widely used to study the role of specific nucleotides or amino acids in genetic elements or proteins, as well as to mimic human genetic diseases.

마우스
Mdm4-C462A
모델명：B6;129S-Mdm4tm1Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-00007
마우스
Muc2-C987Y
모델명：C57BL/6JSmo-Muc2em1C987YSmoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-234203
마우스
Mvd-F250S
모델명：C57BL/6JSmo-Mvdtm(F250S)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-210368
마우스
Myh6-R404Q
모델명：C57BL/6JSmo-Myh6em1(R404Q)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-215054
마우스
Naglu-A198V
모델명：C57BL/6JSmo-Nagluem1(A198V)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-232081
마우스
Naglu-R531X
모델명：C57BL/6JSmo-Nagluem1(R531X)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-232082
마우스
Nefl-N98S
모델명：C57BL/6JSmo-Neflem1(N98S)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-200251
Disease Connection：Charcot-Marie-Tooth disease type 2E
마우스
Nlrp3-LSL-A350V
모델명：C57BL/6JSmo-Nlrp3tm(LSL-A350V)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-210365
마우스
Notch3-R170C
모델명：C57BL/6JSmo-Notch3em1(R170C)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-200254
Disease Connection：CADASIL 1
마우스
Npc1-I1060T
모델명：C57BL/6JSmo-Npc1em1(I1060T)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-18059
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